Against Me! singer Tom Gabel recently made the stunning announcement that he would transition to living as a woman, a revelation that was met with both support and insults. That brave move got us thinking about other artists who've risked their careers -- or in some cases, lives -- to stand up for something or someone. For some musicians, that risk paid off; for others, it severely damaged their careers. From Madonna and Kanye West to Pearl Jam and Lil B, here are 18 artists who've put their careers on the line.
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